Pharming Group N.V. develops and commercialize protein replacement therapies and precision medicines.Ruconest, a recombinant human C1 esterase inhibitor, is used for the treatment of acute hereditary angioedema. RhC1INH, leniolisib, a phosphoinositide 3-kinase delta (PI3K delta) to treat patients with activated PI3K Delta syndrome; and alpha-glucosidase therapy for the. treatment of pompe and fabry diseases.